Target Professions: DO, MD, Nurse, Nurse Practitioner, Physician Assistant
Target Specialties: Rheumatology
Credits Available: 4.75 AMA PRA Category 1 Credits

Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, can prove challenging to address in real-world settings. Although biologics directed against TNF-α can rapidly and sustainably induce clinical remission of these conditions, they have incomplete efficacy; many other conventional treatments used alongside biologics additionally have complex safety profiles that limit their use. These limitations have spurred the development and examination of novel agents, such as Janus Kinase (JAK) inhibitors, in patients with inadequately controlled disease. Through this three-part, small-group educational program, rheumatologists and other supporting healthcare providers can gain greater familiarity with the mechanisms of action behind different JAK inhibitors, evaluate their efficacy and safety in different patient populations, and become acquainted with strategies to improve access to these agents on behalf of their patients. In doing so, clinicians can ensure that the next generation of therapies for immune-mediated inflammatory diseases are used to their fullest potential.


CME/CE Accreditation Information

Itinerary

Part 1

Treating Immune-Mediated, Inflammatory Diseases with JAK Inhibitors - Baseline Assessment

Answer the following questions to assess your knowledge of JAK inhibitors as they are used to treat patients with immune-mediated, inflammatory diseases.

Module 1 - Examining Janus Kinase Inhibitors' Mechanisms of Action

This first self-study module is designed to enhance your understanding of Janus kinase (JAK) inhibition.

Module 2 - The Updated Safety and Efficacy Story of Janus Kinase Inhibitors

This second self-study module is designed to increase your familiarity with late-stage clinical trial data for Janus kinase inhibitors.

Module 3 - Securing Access to Janus Kinase Inhibitors for Patients with Rheumatic Diseases

Identify and familiarize yourself with strategies to limit the frequency of adverse events tied to JAK inhibitors and improve access to JAK inhibitors for patients with rheumatic diseases.

Treating Immune-Mediated, Inflammatory Diseases with JAK Inhibitors - Final Assessment

Answer the following questions to assess your knowledge on the use of JAK inhibitors to treat patients with immune-mediated, inflammatory diseases.

Live Group Discussion 1

This live group discussion focuses on the educational content of the self-study modules that examined the mechanisms of action for JAK inhibitors, efficacy and safety data of JAK inhibitors in patients with immune-mediated, inflammatory diseases, and strategies to improve JAK inhibitor access.

Part 2

Patient Case 1 – a 40-year-old female

This activity features a 40-year-old female who presents with symptoms of uncontrolled RA. This patient activity focuses on clinical considerations in the treatment-refractory setting.

Patient Case 2 – a 60-year-old male

This activity features a 60-year-old male who presents with symptoms of uncontrolled PsA while having multiple medical comorbidities. It focuses on balancing risks and benefits with therapy in treatment-refractory settings.

Your Action Plan to Treat Immune-Mediated, Inflammatory Disorders with JAK Inhibitors

In light of the information reviewed and discussed during this program, please share an action plan that you will implement to improve the diagnosis and management for your patients who are eligible for treatment with JAK inhibitors.

Live Group Discussion 2

This live group discussion is focused on the case studies found in the Group Challenges, which explore how to best use JAK inhibitors in the treatment of patients with immune-mediated, inflammatory diseases.

Interested in becoming a Group Leader?

Requirements:
Ideal Group Leaders should be Rheumatologists, and Rheumatology Advanced Practice Providers. Apply Now

Interested in participating in this curriculum? You can join one of the following groups:

JS
Julia Swafford, PA-C
PA
Rajat Bhatt, MD
Rheumatologist